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hematologyanalyser.myby AA Alive Sdn Bhd
ENBM

Also called: 5 part hematology analyzer, 5-part diff analyser, 5 part CBC machine

5-Part Haematology Analyser: Technology, Parameters and Upkeep

How a 5-part analyser separates the five white-cell types, what it adds to the report, and what it asks of your lab every day.

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How a 5-part analyser classifies white cells

Laser flow cytometry

Cells pass single file through a laser beam in a flow cell. Light scattered at different angles reflects each cell’s size and internal complexity; some analysers add fluorescent dyes that stain nucleic acid to separate cell types more clearly.

Cytochemistry

Some analysers use staining reactions — for example a peroxidase stain — combined with light measurement to tell the white-cell types apart.

Impedance and haemoglobin

Most 5-part analysers still count and size red cells and platelets by impedance and measure haemoglobin photometrically, as a 3-part analyser does.

What the extra parameters add

A 5-part analyser typically reports about 23–30+ parameters, depending on the model.

ResultWhy labs use it
Neutrophils (count and %)Bacterial infection and monitoring of low neutrophil counts
LymphocytesViral infection and lymphocyte disorders
MonocytesChronic infection and recovery after illness
EosinophilsAllergy and parasitic infection
BasophilsRarely raised; noted in some blood disorders
Extended parameters on some modelsFor example immature granulocytes, reticulocytes or nucleated red cells — check the specification

Reagents and maintenance

  • Usually 4–6 reagents: a diluent, more than one lysing reagent, a stain or dye and a cleaner.
  • Some reagents are sensitive to light or temperature — store them exactly as the label says.
  • Daily start-up and shutdown, plus periodic cleaning at the interval the manufacturer sets.
  • The optical system needs engineer service visits; ask how often and who does them in your state.
  • More parameters to watch on QC, with controls that carry 5-part target values.
  • More reagent used in fixed daily cycles, so cost per test rises sharply at low volume.

Read next Reagents, storage and stabilityQC and calibration guide

Who needs a 5-part analyser

  • Hospital and private laboratories with high daily volume and many abnormal samples.
  • Specialist centres that need eosinophil, monocyte and basophil counts routinely.
  • Labs that want the analyser to classify more cells so fewer normal samples need a manual film.

Read next Still deciding? 3-part vs 5-part

Related guides

3-Part vs 5-Part Haematology AnalyserBoth run a full blood count; they differ in how finely they split the white cells — and in what they cost to run every day.Haematology Analyser Quality Control and CalibrationThe routine that keeps every FBC result trustworthy — from the morning control run to external quality assessment and accreditation.Hematology Analyzer Reagents: What They Do and How to Store ThemReagents are the largest recurring cost of an FBC machine and a common source of QC problems. Here is how to choose, store and use them.

Hematology Analyser supply near you

Delivery, installation and training across Malaysia from Batu Caves, Kota Kinabalu and Kuching.

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Frequently asked questions

Does a 5-part analyser eliminate blood films?
No. It reduces manual films for normal samples, but flagged samples — for example suspected blasts or atypical cells — still need a film reviewed by trained staff.
How many reagents does a 5-part haematology analyser use?
Usually four to six, including a diluent, more than one lysing reagent, a stain or dye and a cleaner. The exact set depends on the model.
Is a 5-part analyser harder to maintain?
Somewhat. The optical system and extra reagents mean more cleaning steps and more QC parameters to watch, so plan for trained staff and a reliable service engineer.

Get a written quotation

Tell us your clinic or lab type, daily workload and location. We match suitable models and send a written quotation with delivery, installation and training spelled out.